Gynaecology

GYNAECOLOGY

The branch of physiology and medicine which deals with the functions and diseases specific to women and girls, especially those affecting the reproductive system.

Rhoclone

Rhoclone is a Monoclonal Human Anti-rhesus Immunoglobulin (lgG1) containing antibodies to Rho-D. It is derived from stable hybridoma cell line and purified using chromatography. It is available as both lyophilized and liquid formulation.

Category - Immunoglobulins

Indications - Prevents Rho-D negative women forming antibodies to foetal rhesus-positive red blood cells that may pass into the maternal blood during childbirth, abortion or certain other sensitising events.

Dosage & Administration - Please refer pack insert for further details

Presentation - 100 mcg / 150 mcg / 300 mcg (lyophilized / liquid)

Storage - 2- 8°C

Endoprost

"ENDOPROST is a clear colourless sterile aqueous solution of Carboprost Tromethamine for Intramuscular Injection. Carboprost is a synthetic 15 methyl analogue of naturally occurring prostaglandin F2α."

Category - Prostaglandin Analogue

Indications - Prevention & Treatment of Post Partum Hemorrhage

Dosage & Administration - Please refer pack insert for further details

Presentation - "ENDOPROST - 0.5ml Vial : Each 0.5ml containing Carboprost Tromethamine equivalent to 125 mcg of Carboprost. ENDOPROST - 1ml Vial : Each ml containing Carboprost Tromethamine equivalent to 250 mcg of Carboprost."

Storage - 2- 8°C

Luprodex 3.75/11.50

LUPRODEX 3.75 mg (DEPOT) is a sterile lyophilized powder containing Leuprolide Acetate formulated as Microspheres. LUPRODEX 3.75 mg (DEPOT) is to be reconstituted with accompanying diluent which forms a uniform suspension, intended for intramuscular or subcutaneous injection to be administered once every month.

Category - GnRH analog

Indications
1) Endometriosis
2) Uterine leiomyomata
3) Advanced Prostate Cancer
4) Central Precocious Puberty

Dosage & Administration - Please refer pack insert for further details

Presentation - 3.75mg vial

Storage - Store below 25°C. Protect from light. Do not freeze

Primigyn

Primigyn (Dinoprostone) Gel 0.5 mg is a naturally-occurring Prostaglandin E2 (PGE2). In pregnancy, PGE2 is secreted continuously by the fetal membranes and placenta and plays an important role in the final events leading to the initiation of labor. It is known that PGE2 stimulates the production of PGF2 which in turn sensitizes the myometrium to endogenous or exogenously administrated oxytocin, this stimulation of the myometrium of the gravid uterus causes it to contract in a manner similar to contractions seen in the term uterus during labor.

Category - Prostaglandin E2

Indications - For ripening and dilatation of an unfavorable cervix for labour induction.

Dosage & Administration - Please refer pack insert for further details

Presentation - 0.5 mg Dinoprostone BP per 3.0 g gel in a syringe with a catheter for endocervical application.

Storage - 2- 8°C

Hucog HP

Hucog HP is brand of Human Chorionic Gonadotrophin hormone (Highly Purified). It is a time tested quality product. No reconstitution required with ease of administration. It is the only liquid stable HCG in India. It is available as lyophilized formulation in few markets.

Category - GONADOTROPINS

Indications - Anovulatory infertility : In the female, HUCOG HP is used in the treatment of anovulatory infertility. where its administration would form part of recognized treatment regimen involving prior stimulation of follicular maturation and endometrial proliferation e.q. with Menotropin Injection (HUMOG HP). Hypogonadotrophin hypogonadism and cryptorchidism : In the male, HUCOG HP stimulates the interstitial cells of the testes and consequently the secretion of androgens and the development of secondary sexual characteristics. With concomitant Menotropin Injection therapy, HUCOG HP stimulates the induction and maintenance of spermatogenesis.

Dosage & Administration - Please refer pack insert for further details

Presentation - 2000/5000/10000 IU (Liquid and Lyophilised)

Storage - 2- 8°C

Evafact

"Evafact is a clear colourless sterile aqueous solution of Carboprost Tromethamine for Intramuscular Injection. Carboprost is a synthetic 15 methyl analogue of naturally occurring prostaglandin F2α."

Category -

Indications - Evafact is indicated for the management of pelvic pain associated with endometriosis.

Dosage & Administration - Please refer pack insert for further details

Presentation - Evafact is a white to off white tablet containing 2 mg Dienogest for oral use. It also contains Lactose, Microcrystalline Cellulose, Starch, Magnesium Stearate, Talcum and Crospovidone as an excipients.

Storage - Store protected from light & moisture, at a temperature not exceeding 25°C.

Miprogen Capsules

MIPROGEN Gel is a bioadhesive vaginal gel containing micronized progesterone in an emulsion system, which is contained in single use, polypropylene ® vaginal applicators. Each applicator delivers 1.125 grams of MIPROGEN Gel containing 90mg (8% gel) of progesterone. The gel also contains Glycerine, Carbopol 974, Polycarbophil, Gelucire 43/01 . It has the appearance of a soft, white coloured gel.

Category -

Indications - MIPROGEN Gel is indicated for progesterone supplementation or replacement as part of an Assisted Reproductive Technolongy ("ART") treatment for infertile women with progesterone deficiency.

Dosage & Administration - Please refer pack insert for further details

Presentation - MIPROGEN Gel is available in single use prefilled polypropylene applicator, each providing 1.125 g Gel containing 90 mg Progesterone.

Storage - Store below 25ºC. Do not freeze.

Miprogen SR

MIPROGEN contains progesterone and is identical to progesterone of human ovarian origin. MIPROGEN is for vaginal / rectal / oral administration.

Category -

Indications - Vaginal / Rectal and Oral

Dosage & Administration - Please refer pack insert for further details

Presentation - MIPROGEN is available as 100 mg, 200 mg and 400 mg in blister pack of 10 capsules.

Storage - Store in a cool, dry and dark place.

Lonopin

Lonopin is a sterile aqueous solution containing Enoxaparin Sodium, a Low Molecular Weight Heparin (LMWH), in single dose ready-to-use prefilled syringes intended for subcutaneous or intravascular use.

Category -

Indications - Abdominal Surgery, Hip or Knee Replacement Surgery, Medical Patients During Acute Illness

Dosage & Administration - Please refer pack insert for further details

Presentation - Lonopin 20mg: Each carton comprises 1 Pre-filled Syringe containing 20mg (2000 anti-Xa I.U. / 0.2mL) Enoxaparin sodium in a blister pack along with a pack insert.

Storage - Store below 25 C. Do not freeze.

BHARGLOB

BHARGLOB® injection is a solution of immunoglobulins active against pathogens normally occurring in the population. BHARGLOB® is prepared from the plasma of healthy human volunteers stringently screened to ensure absence of any viruses and pathogens.

Category - IMMUNOGLOBULINS

Indications - PROPHYLAXIS : Who have had no opportunity of gaining immunity by natural means or by active immunisation and who are at risk. SUBSTITUTION : Congential or acquired agammaglobulinemia or hypogammaglobulinemia, where the normal response to an immunogenic stimulus is impaired.

THERAPY : In patients suffering from generalised infections including hepatitis, mumps, measles, varicella, bronchial asthma and allergic manifestations combined with bronchial infections.

Dosage & Administration - Please refer pack insert for further details

Presentation - 10% solution in vials of 1ml / 2ml 16.5% solution in vials of 1ml / 2ml

Storage - 2- 8°C.